Binding of tolbutamide to glycated human serum albumin
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چکیده
منابع مشابه
Binding of tolbutamide to glycated human serum albumin.
The presence of elevated levels of glucose in blood during diabetes can lead to the non-enzymatic glycation of serum proteins such as human serum albumin (HSA). This study examined the changes that occur in binding of the sulfonylurea drug tolbutamide to HSA as the level of glycation for this protein was increased. High-performance affinity chromatography was used in this work along with column...
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ژورنال
عنوان ژورنال: Journal of Pharmaceutical and Biomedical Analysis
سال: 2011
ISSN: 0731-7085
DOI: 10.1016/j.jpba.2010.09.003